Designed to deter the signs of aging, reduce the effects of fatigue on your face, hydrate, and soothe, Wyoming-born skincare brand Caldera Lab's The Base Layer is one of the best all-around facial moisturizers for men. Simply apply a dime-size amount every morning after washing your face and watch the effective formula nourish and protect your skin without leaving you looking greasy or clogged. And these are more than just blanket statements — they're backed by research. During a two-month trial period, over 90% of men appeared younger-looking and with fewer fine lines and wrinkles.